Mixtral 8x7B Instruct on B200 180GB (180GB) — VRAM, KV Cache & Throughput

Mixtral 8x7B Instruct (46.7B total, 12.9B active, Sparse MoE + GQA) uses 26.42 GiB of 4-bit weights (Q4_K_M), requiring 27.98 GiB total at 8K context and 30.98 GiB at 32K on B200 180GB (~240.9 tok/s decode).

Interactive Sizing Workbench

Full Compatibility Report →

Open-Weight Model46.7B / 12.9B

Weights & QuantizationQ4_K_M · 26.42 GiB

Context Window8,192 (8K)

Target Hardware

180 GB · 8000 GB/s

GPU Count (Tensor Parallel)

Concurrent Batch Size

KV Cache Precision

Inference Engine

System RAM Offload (CPU)0%

Fits with Safe Headroom

Config-derived formula HF config.json ↗

Memory Allocation Breakdown (GiB) 27.98 GiB (30.04 GB) / 180 GiB (16%)

Model Weights: 26.42 GiB KV Cache & State: 1 GiB Runtime & Activation Buffers: 0.56 GiB System RAM Offload: 0 GiB

Required GPU Memory

27.98 GiB

30.04 GB (decimal)

Usable Hardware Memory

171 GiB

180 GB (physical)

Safe Headroom

+143.02 GiB

16% utilization

Est. Decode Throughput

~240.9 tok/s

12.9B active params

Est. Prefill Throughput

~24000 tok/s

4K Prompt TTFT: ~171 ms

Est. Cost / 1M Tokens

$0.38

Sparse MoE + GQA · Apache-2.0

Recommended Hardware for Current Configuration

Best Single GPU

Radeon AI PRO R9700 32GB (32GB)

~$1,299

Best Value / Used GPU

RTX A6000 (48GB)

~$4,500

Apple Unified Memory

Ryzen AI Max+ 395 128GB

~$1,999

Cloud From

RunPod · $0.33 / hr

1x RTX A6000

Production Launch Commands

llama.cpp (GGUF)

llama-server -hf mistralai/Mixtral-8x7B-Instruct-v0.1:Q4_K_M \
  --ctx-size 8192 -ngl 999 --flash-attn

vLLM

vllm serve mistralai/Mixtral-8x7B-Instruct-v0.1 \
  --max-model-len 8192 --gpu-memory-utilization 0.92

Live Token Speed Simulator (TTFT ~171ms · ~240.9 tok/s)

[Mixtral 8x7B Instruct · 27.98 GiB] allocated on target GPU. Prefill completed in TTFT window; streaming autoregressive tokens at memory-bandwidth-bound rate...

Cloud GPU Comparison & Rent-vs-Buy TCO

Verified public rates across RunPod, Vast.ai, Vultr, and DigitalOcean.

Verified: 2026-11-04

Active usage (hours / day)4 h / day

Local hardware budget ($)

Electricity rate ($/kWh)

Purchase break-even

~38.5 months

Est. local power: $6.38 / mo

Provider	Recommended Instance	Total VRAM	Hourly Rate	Monthly at Selected Hours	Billing Mode	Deploy
RunPod	1x RTX A6000 (Community Cloud)	48 GB	$0.33 / hr	$40.13 / mo	Per-second	Deploy GPU ↗
Vast.ai	1x A100 80GB SXM (Verified Host · SXM4)	80 GB	$0.44 / hr	$53.75 / mo	Spot / On-demand	Deploy GPU ↗
*Vultr ($300 Free Credit)**	1x L40S 48GB (Dedicated Instance · $300 Credit*)	48 GB	$1.67 / hr	$203.19 / mo	Hourly	Deploy GPU ↗
Vultr Cloud GPU	1x L40S 48GB (Dedicated Instance)	48 GB	$1.67 / hr	$203.19 / mo	Hourly	Deploy GPU ↗
DigitalOcean	1x RTX 6000 Ada (Dedicated Instance)	48 GB	$1.57 / hr	$190.91 / mo	Per-second	Deploy GPU ↗

Rates reflect public listings on the verification date and fluctuate with regional inventory.

Fine-Tuning VRAM Requirements (QLoRA / LoRA / Full) — Mixtral 8x7B Instruct

QLoRA (4b) Fits with Safe Headroom

29.31 GiB

Model Weights: 26.42 GiB · Gradients + Optimizer: 1.81 GiB · Act: 1.08 GiB

Recommended GPU: Radeon AI PRO R9700 32GB (32GB)

LoRA (16b) Fits with Safe Headroom

91.26 GiB

Model Weights: 86.99 GiB · Gradients + Optimizer: 2.84 GiB · Act: 1.43 GiB

Recommended GPU: Instinct MI300X 192GB (192GB)

Full BF16 Exceeds Available GPU Memory

359.18 GiB

Model Weights: 86.99 GiB · Gradients + Optimizer: 269.67 GiB · Act: 2.52 GiB

Recommended GPU: 4x H200 141GB SXM (564GB)

Engineering Sizing Notes & Optimization Playbook

Quick Hardware Verdict

B200 180GB (180GB physical, 171 GiB usable) runs 4-bit (Q4_K_M) Mixtral 8x7B Instruct at 8K context using 27.98 GiB with 143.02 GiB of safe headroom (~240.9 tok/s single-stream decode).

KV Cache & Runtime Tuning

Mixtral 8x7B Instruct uses Sparse MoE + GQA (46.7B total, 12.9B active per token). Moving from 8K to 32K context expands FP16 KV cache from 1 GiB to 4 GiB; enabling 8-bit KV cache (llama.cpp -ctk q8_0 -ctv q8_0 or vLLM --kv-cache-dtype fp8) saves 2 GiB at 32K (reducing total VRAM to 28.98 GiB).

VRAM Scaling Across Context Windows (4K to 128K, 4-bit Weights)

Model weights remain constant while attention KV cache grows with context length and batch size.

Quantization Precision & Memory Matrix — Mixtral 8x7B Instruct @ 8K

Quantization Format	Weights (GiB)	KV Cache	Total VRAM (GiB)	Decode Speed	Compatibility (B200 180GB)	Recommended GPU	Data Source
Native Weights (BF16 / FP8 / MXFP4 — Lossless) (BF16)	86.99 GiB	1 GiB	88.55 GiB (95.08 GB)	~118 tok/s	Fits with Safe Headroom	Instinct MI300X 192GB (192GB)	Official checkpoint size
FP8 / GGUF Q8_0 (8-bit — Near-Lossless) (Q8_0)	46.21 GiB	1 GiB	47.77 GiB (51.29 GB)	~179.7 tok/s	Fits with Safe Headroom	RTX PRO 6000 Blackwell (96GB)	Config-derived formula
GGUF Q6_K (6-bit — High Precision) (Q6_K)	35.66 GiB	1 GiB	37.22 GiB (39.96 GB)	~207.9 tok/s	Fits with Safe Headroom	A40 48GB (48GB)	Config-derived formula
GGUF Q5_K_M (5-bit — Balanced) (Q5_K_M)	30.96 GiB	1 GiB	32.52 GiB (34.92 GB)	~223.5 tok/s	Fits with Safe Headroom	A40 48GB (48GB)	Config-derived formula
Q4_K_M / UD-Q4_K_XL / AWQ (4-bit — Recommended) (Q4_K_M)	26.42 GiB	1 GiB	27.98 GiB (30.04 GB)	~240.9 tok/s	Fits with Safe Headroom	Radeon AI PRO R9700 32GB (32GB)	Config-derived formula
GGUF IQ4_XS (4.25-bit — Compact) (IQ4_XS)	23.14 GiB	1 GiB	24.7 GiB (26.52 GB)	~255.3 tok/s	Fits with Safe Headroom	Radeon AI PRO R9700 32GB (32GB)	Config-derived formula
GGUF Q3_K_M (3-bit — Low VRAM) (Q3_K_M)	21.29 GiB	1 GiB	22.85 GiB (24.54 GB)	~264.2 tok/s	Fits with Safe Headroom	Radeon AI PRO R9700 32GB (32GB)	Config-derived formula
GGUF UD-Q2_K_XL (2-bit — Extreme MoE) (UD-Q2_K_XL)	15 GiB	1 GiB	16.56 GiB (17.78 GB)	~299.8 tok/s	Fits with Safe Headroom	Arc Pro B60 24GB (24GB)	Config-derived formula

Technical Specifications & FAQ

Does Mixtral 8x7B Instruct fit on B200 180GB (180GB)?

In 4-bit (Q4_K_M) at 8,192 context, Mixtral 8x7B Instruct requires 27.98 GiB total GPU memory (26.42 GiB weights + 1 GiB KV cache + 0.56 GiB runtime buffers) against 171 GiB usable on B200 180GB, delivering ~240.9 tok/s decode.

How much VRAM does Mixtral 8x7B Instruct need at 32K context?

At 32,768 context tokens, Mixtral 8x7B Instruct (Sparse MoE + GQA) allocates 4 GiB for KV cache and state, bringing total 4-bit VRAM to 30.98 GiB (33.26 GB decimal).

Evaluate This Model on Other GPUs

RTX 3060 12GB (12GB)RTX 4060 Ti 16GB (16GB)RTX 4070 Ti Super (16GB)RTX 4080 Super (16GB)RTX 5070 12GB (12GB)RTX 5070 Ti (16GB)RTX 5080 (16GB)RTX 3090 (24GB)RTX 4090 (24GB)RTX 4090 D (24GB)RTX 5090 (32GB)RTX 5090 D (32GB)RTX A6000 (48GB)RTX 6000 Ada (48GB)RTX PRO 6000 Blackwell (96GB)DGX Spark (GB10 128GB) (128GB)L4 24GB (24GB)A40 48GB (48GB)L20 48GB (48GB)L40S 48GB (48GB)A800 80GB SXM (80GB)A100 80GB SXM (80GB)H800 80GB SXM (80GB)H100 80GB SXM (80GB)H20 96GB HBM3 (96GB)H20 141GB HBM3e (141GB)H200 141GB SXM (141GB)B300 288GB Blackwell Ultra (288GB)Ascend 910B 64GB (昇腾) (64GB)Ascend 910C 128GB (昇腾) (128GB)Atlas 300I Duo 96GB (310P) (96GB)MLU590 80GB (寒武纪思元) (80GB)DCU K100-AI 64GB (海光深算) (64GB)MetaX C500 64GB (沐曦曦云) (64GB)Kunlunxin P800 64GB (昆仑芯) (64GB)MTT S4000 48GB (摩尔线程) (48GB)Radeon RX 7900 XTX 24GB (24GB)Radeon AI PRO R9700 32GB (32GB)Ryzen AI Max+ 395 128GB (128GB)Instinct MI300X 192GB (192GB)Instinct MI325X 256GB (256GB)Instinct MI355X 288GB (288GB)Arc Pro B60 24GB (24GB)Gaudi 3 128GB HBM2e (128GB)Mac mini M4 Pro 64GB (64GB)MacBook Pro M4 Max 128GB (128GB)Mac Studio M4 Ultra 256GB (256GB)Mac Studio M3 Ultra 512GB (512GB)

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